How to take Degludec. Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended. A dose counter on the injection pen shows your dose in units. Do not convert your dose. Insulin is injected under the skin. You will be shown how to use injections at home. Do not give yourself this medicine if you do not understand how to use the injection and properly dispose of used needles and syringes. Insulin degludec must not be given with an insulin pump, or mixed with other insulins. Do not inject insulin degludec into a vein or a muscle.