What is Plaquenil? Plaquenil (Hydroxychloroquine) belongs to a group of medicines called quinolines. Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. This medicine is not effective against all strains of malaria. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus.
How to take Plaquenil. To prevent malaria in adults, two tablets are typically taken once a week, on the same day each week. The first dose of Plaquenil is usually taken one to two weeks before traveling to an area where malaria is prevalent. Doses are then continued for four weeks after exposure. If two weeks’ time is not available before you will be exposed to malaria, talk to a doctor about how much to take. Usually the initial dose is doubled. To treat an attack of malaria in adults, four tablets are usually taken right away. After that, two tablets are taken six to eight hours later, followed by two tablets on each of the next two days.