Tizanidine Overview, Dosage, How to Take, Side Effects and Overdose

What is Tizanidine? Tizanidine is a short-acting muscle relaxer. It works by blocking nerve impulses (pain sensations) that are sent to your brain. Tizanidine is used to treat spasticity by temporarily relaxing muscle tone. Tizanidine may also be used for purposes not listed in this medication guide.

Tizanidine dosage:

  • Initial dose: 2 mg orally every 6 to 8 hours as needed. Peak effects occur in approximately 1 to 2 hours and last for 3 to 6 hours; treatment can be repeated as needed to a maximum of 3 doses in 24 hours; gradually increase dose by 2 to 4 mg at intervals of 1 to 4 days until satisfactory reduction of muscle tone is achieved
  • Maximum single dose: 16 mg
  • Maximum daily dose: 36 mg in 24 hours